Csnk2a1 cancer
WebApr 1, 2024 · Functionally crucial for cell development and commonly dysregulated in cancer, CSNK2 is a pleiotropic serine/threonine kinase encoded by two distinct catalytic … WebFeb 7, 2011 · Description Casein kinase II is a serine/threonine protein kinase that phosphorylates acidic proteins such as casein. It is involved in various cellular processes, including cell cycle control, apoptosis, and circadian rhythm. The kinase exists as a tetramer and is composed of an alpha, an alpha-prime, and two beta subunits.
Csnk2a1 cancer
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WebSep 19, 2024 · Fusogenic peptide delivery of bioactive siRNAs targeting CSNK2A1 for treatment of ovarian cancer Mol Ther Nucleic Acids. 2024 Sep 19;30:95-111. doi: 10.1016/j.omtn.2024.09.012. eCollection 2024 Dec 13. Authors WebFeb 5, 2024 · The promoter of the well-known CK2α, CSNK2A1, displays characteristics of a housekeeping gene, whereas CSNK2A3 has a characteristic of a regulated promoter with two TATA boxes and a CAAT box. GPR68, a family of the G protein-coupled receptors, is also known as ovarian cancer G protein-coupled receptor 1 (OGR1).
WebSep 30, 2024 · Cholangiocarcinoma (CCA), accounting for about 15% of primary liver cancer, is the second most prevalent cancer after hepatocellular carcinoma (HCC) [].CCA is a highly lethal malignancy in the biliary tree, and its incidence and mortality continue to increase [2,3].Currently, the prognosis of CCA is poor, with a 5-year overall survival (OS) … WebJun 11, 2024 · Our results reveal that CSNK2A1-dependent HMGA2 phosphorylation may partially underlie cisplatin-resistance in cervical cancer, suggesting that HMGA2 phosphorylation may have potential as …
WebApr 11, 2024 · Direct alteration of RBPs by mutation is relatively rare in cancer (Gebauer et al, 2024), so a key question concerns the mechanistic link between mutations in cancer driver genes and the resulting dysregulation of RBPs. In this study, we used an inducible mouse model of PDAC, combined with a whole-transcriptome quantitative RIC approach, … WebObjective: Casein kinase 2 a1 (CSNK2A1) has been shown to be involved in tumorigenesis by enhancing several oncogenic signaling pathways in various cancers. However, the function and mechanism of CSNK2A1 in …
WebCSNK2A1 has been found to be related to the invasion and migration of various cancer cells through epithelial-mesenchymal transition (EMT) 24 and nuclear factor-kappa B (NF-κB) 16,20 signaling pathways, but the …
WebCSNK2A1 Foundation Appoints Dr. Gabrielle Rushing As Science Program Director ... the Cancer Research Institute and other world class organizations attending the upcoming #aacr2024 starting 1 week ... dvt phaseWebThis section gives an overview of CSNK2A1, along with links to any related data and resources. Census gene Curated gene Mouse gene Hallmark gene COSMIC gene CSNK2A1 (COSG646561) Genomic coordinates 20:472498..543835 (negative strand) Synonyms Cka1, Cka2, CCDS13003.1, ENSG00000101266.18, NM_001895.3, … crystal city ca weatherWebApr 30, 2024 · Additionally, a limitation of essentially all targeted anti-cancer therapies is the onset of treatment-induced acquired resistance (17,18). In response to pharmacologic inhibition of a key cancer driver, cancer cells can induce a complex array of responses that functionally compensate for target inhibition. dvt pe prophylaxis icd 10WebDec 13, 2024 · CSNK2A1 is an oncogene found overexpressed in several cancer types, including ovarian cancer, and is responsible for increased growth and cell survivability in … crystal city cavesWebDec 13, 2024 · CSNK2A1 is an oncogene found overexpressed in several cancer types, including ovarian cancer, and is responsible for increased growth and cell survivability in the presence of chemotherapeutic agents.27,28 The protein encoded by CSNK2A1, CK2α, plays a major role in cell cycle regulation, cell-cell communication, DNA repair activation, … crystal city caveWebExpression of CSNK2A1 (Cka1, Cka2) in cancer tissue. The cancer tissue page shows antibody staining of the protein in 20 different cancers. dvt personal history icd 10WebDec 2, 2024 · Stable cancer cell lines with CSNK2A1 gene overexpression or knockdown were established to investigate the function and mechanism of CSNK2A1 in GC cells. … crystal city cave mo